STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GNA12G protein subunit alpha 12. (381 aa)    
Predicted Functional Partners:
ARHGEF12
Rho guanine nucleotide exchange factor 12.
    
 0.992
ARHGEF11
Rho guanine nucleotide exchange factor 11.
    
 0.987
GNA13
G protein subunit alpha 13.
  
 
0.985
S1PR2
Sphingosine-1-phosphate receptor 2; Belongs to the G-protein coupled receptor 1 family.
    
 0.977
RHOA
Uncharacterized protein.
    
 0.972
LPAR6
Lysophosphatidic acid receptor 6; Belongs to the G-protein coupled receptor 1 family.
    
 0.963
S1PR3
Sphingosine-1-phosphate receptor 3; Belongs to the G-protein coupled receptor 1 family.
    
 0.963
ADRA1A
Adrenoceptor alpha 1A.
    
 0.962
S1PR4
Sphingosine-1-phosphate receptor 4.
    
 0.959
GNG12
Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
    
 0.956
Your Current Organism:
Macaca fascicularis
NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.