STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SYNE2Spectrin repeat containing nuclear envelope protein 2. (6907 aa)    
Predicted Functional Partners:
SUN2
Sad1 and UNC84 domain containing 2.
    
 0.981
SUN1
Sad1 and UNC84 domain containing 1.
    
 0.950
FHOD1
Formin homology 2 domain containing 1.
    
 
 0.916
LMNA
Lamin A/C; Belongs to the intermediate filament family.
    
 0.807
SYNE1
Spectrin repeat containing nuclear envelope protein 1.
     
0.752
SUN3
SUN domain-containing protein 3; As a probable component of the LINC (LInker of Nucleoskeleton and Cytoskeleton) complex, involved in the connection between the nuclear lamina and the cytoskeleton. The nucleocytoplasmic interactions established by the LINC complex play an important role in the transmission of mechanical forces across the nuclear envelope and in nuclear movement and positioning. May be involved in nuclear remodeling during sperm head formation in spermatogenenis. A probable SUN3:SYNE1 LINC complex may tether spermatid nuclei to posterior cytoskeletal structures such as [...]
    
 0.707
TMEM67
Transmembrane protein 67.
    
 
 0.702
FHOD3
Formin homology 2 domain containing 3.
    
 
 0.701
EMD
Emerin.
    
 
 0.671
TBPL2
TATA-box binding protein like 2.
    
 
 0.661
Your Current Organism:
Macaca fascicularis
NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque
Server load: low (14%) [HD]