node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CLPX | LONP2 | ENSMFAP00000018379 | ENSMFAP00000013919 | Caseinolytic mitochondrial matrix peptidase chaperone subunit. | Lon protease homolog 2, peroxisomal; ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import. May indirectly regulate peroxisomal fatty acid beta- oxidation through degradation of the self-processed forms of TYSND1. | 0.718 |
CLPX | YME1L1 | ENSMFAP00000018379 | ENSMFAP00000042400 | Caseinolytic mitochondrial matrix peptidase chaperone subunit. | AAA domain-containing protein. | 0.756 |
ENSMFAP00000015252 | LONP2 | ENSMFAP00000015252 | ENSMFAP00000013919 | Uncharacterized protein. | Lon protease homolog 2, peroxisomal; ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import. May indirectly regulate peroxisomal fatty acid beta- oxidation through degradation of the self-processed forms of TYSND1. | 0.718 |
ENSMFAP00000015252 | YME1L1 | ENSMFAP00000015252 | ENSMFAP00000042400 | Uncharacterized protein. | AAA domain-containing protein. | 0.756 |
ENSMFAP00000045934 | NDUFA13 | ENSMFAP00000045934 | ENSMFAP00000027755 | Rhomboid domain-containing protein. | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Involved in the interferon/all-trans-retinoic acid (IFN/RA) induced cell death. This apoptotic activity is inhibited by interaction with viral IRF1. Prevents the transactivation of STAT3 target genes. May play a role in [...] | 0.616 |
ENSMFAP00000045934 | OMA1 | ENSMFAP00000045934 | ENSMFAP00000020162 | Rhomboid domain-containing protein. | Peptidase_M48 domain-containing protein. | 0.633 |
ENSMFAP00000045934 | STOML2 | ENSMFAP00000045934 | ENSMFAP00000043463 | Rhomboid domain-containing protein. | Stomatin like 2. | 0.679 |
ENSMFAP00000045934 | YME1L1 | ENSMFAP00000045934 | ENSMFAP00000042400 | Rhomboid domain-containing protein. | AAA domain-containing protein. | 0.731 |
LONP2 | CLPX | ENSMFAP00000013919 | ENSMFAP00000018379 | Lon protease homolog 2, peroxisomal; ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import. May indirectly regulate peroxisomal fatty acid beta- oxidation through degradation of the self-processed forms of TYSND1. | Caseinolytic mitochondrial matrix peptidase chaperone subunit. | 0.718 |
LONP2 | ENSMFAP00000015252 | ENSMFAP00000013919 | ENSMFAP00000015252 | Lon protease homolog 2, peroxisomal; ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import. May indirectly regulate peroxisomal fatty acid beta- oxidation through degradation of the self-processed forms of TYSND1. | Uncharacterized protein. | 0.718 |
LONP2 | OMA1 | ENSMFAP00000013919 | ENSMFAP00000020162 | Lon protease homolog 2, peroxisomal; ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import. May indirectly regulate peroxisomal fatty acid beta- oxidation through degradation of the self-processed forms of TYSND1. | Peptidase_M48 domain-containing protein. | 0.472 |
LONP2 | YME1L1 | ENSMFAP00000013919 | ENSMFAP00000042400 | Lon protease homolog 2, peroxisomal; ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import. May indirectly regulate peroxisomal fatty acid beta- oxidation through degradation of the self-processed forms of TYSND1. | AAA domain-containing protein. | 0.679 |
NDUFA13 | ENSMFAP00000045934 | ENSMFAP00000027755 | ENSMFAP00000045934 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Involved in the interferon/all-trans-retinoic acid (IFN/RA) induced cell death. This apoptotic activity is inhibited by interaction with viral IRF1. Prevents the transactivation of STAT3 target genes. May play a role in [...] | Rhomboid domain-containing protein. | 0.616 |
NDUFA13 | PARL | ENSMFAP00000027755 | ENSMFAP00000035550 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Involved in the interferon/all-trans-retinoic acid (IFN/RA) induced cell death. This apoptotic activity is inhibited by interaction with viral IRF1. Prevents the transactivation of STAT3 target genes. May play a role in [...] | Presenilin associated rhomboid like. | 0.769 |
NDUFA13 | TIMMDC1 | ENSMFAP00000027755 | ENSMFAP00000032018 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Involved in the interferon/all-trans-retinoic acid (IFN/RA) induced cell death. This apoptotic activity is inhibited by interaction with viral IRF1. Prevents the transactivation of STAT3 target genes. May play a role in [...] | Translocase of inner mitochondrial membrane domain containing 1. | 0.979 |
NDUFA13 | YME1L1 | ENSMFAP00000027755 | ENSMFAP00000042400 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Involved in the interferon/all-trans-retinoic acid (IFN/RA) induced cell death. This apoptotic activity is inhibited by interaction with viral IRF1. Prevents the transactivation of STAT3 target genes. May play a role in [...] | AAA domain-containing protein. | 0.939 |
OMA1 | ENSMFAP00000045934 | ENSMFAP00000020162 | ENSMFAP00000045934 | Peptidase_M48 domain-containing protein. | Rhomboid domain-containing protein. | 0.633 |
OMA1 | LONP2 | ENSMFAP00000020162 | ENSMFAP00000013919 | Peptidase_M48 domain-containing protein. | Lon protease homolog 2, peroxisomal; ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import. May indirectly regulate peroxisomal fatty acid beta- oxidation through degradation of the self-processed forms of TYSND1. | 0.472 |
OMA1 | PARL | ENSMFAP00000020162 | ENSMFAP00000035550 | Peptidase_M48 domain-containing protein. | Presenilin associated rhomboid like. | 0.650 |
OMA1 | YME1L1 | ENSMFAP00000020162 | ENSMFAP00000042400 | Peptidase_M48 domain-containing protein. | AAA domain-containing protein. | 0.716 |