STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SULT1C4Sulfotransferase; Belongs to the sulfotransferase 1 family. (302 aa)    
Predicted Functional Partners:
CBR3
Carbonyl reductase 3; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
      
 0.642
AOX1
Aldehyde oxidase 1; Oxidase with broad substrate specificity, oxidizing aromatic azaheterocycles, such as N1-methylnicotinamide, N-methylphthalazinium and phthalazine, as well as aldehydes, such as benzaldehyde, retinal, pyridoxal, and vanillin. Plays a key role in the metabolism of xenobiotics and drugs containing aromatic azaheterocyclic substituents. Participates in the bioactivation of prodrugs such as famciclovir, catalyzing the oxidation step from 6-deoxypenciclovir to penciclovir, which is a potent antiviral agent. Is probably involved in the regulation of reactive oxygen specie [...]
   
  
 0.622
AKR1C1-2
Aldo_ket_red domain-containing protein.
   
  
 0.560
CHST6
Sulfotransferase; Belongs to the sulfotransferase 1 family.
   
  
 0.538
AKR1C1
Aldo-keto reductase family 1 member C1 homolog; Converts progesterone to its inactive form, 20-alpha- dihydroxyprogesterone (20-alpha-OHP). In the liver and intestine, may have a role in the transport of bile. May have a role in monitoring the intrahepatic bile acid concentration. May play a role in myelin formation. Can oxidize both 20-alpha- and 3-alpha-hydroxysteroids. Low activity towards 5-alpha-androstan-17-beta-ol-3-one. Can also act on non-steroidal substrates such as S-indan-1-ol, S-tetralol and 4- chromanol; Belongs to the aldo/keto reductase family.
   
  
 0.533
UGT2A3
UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family.
   
  
 0.530
NDST1
N-deacetylase and N-sulfotransferase 1.
      
 0.522
SULT2B1
Sulfotransferase; Belongs to the sulfotransferase 1 family.
  
0.503
CYP2B6
Cytochrome P450 2B6; Belongs to the cytochrome P450 family.
   
  
 0.503
SULT2A1
Bile salt sulfotransferase; Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfonation of steroids and bile acids in the liver and adrenal glands.
  
0.502
Your Current Organism:
Macaca fascicularis
NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque
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