STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BOKBCL2 family apoptosis regulator BOK. (212 aa)    
Predicted Functional Partners:
BID
BH3 interacting domain death agonist.
    
 0.755
BAD
BCL2 associated agonist of cell death.
   
 0.740
BCL2L11
Bcl-2-like protein 11; Induces apoptosis and anoikis. Belongs to the Bcl-2 family.
    
 0.735
BECN1
Beclin 1.
    
 
 0.650
APAF1
Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.
    
 
 0.637
BBC3
BCL2 binding component 3.
   
 0.623
MCL1
Uncharacterized protein.
    
 
 0.619
TSNARE1
t-SNARE domain containing 1.
      
 0.612
BNIP3
BCL2 interacting protein 3.
    
 
 0.558
BMF
Bcl2 modifying factor.
    
 0.555
Your Current Organism:
Macaca fascicularis
NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.