STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACE2Angiotensin-converting enzyme. (805 aa)    
Predicted Functional Partners:
DPP4
Dipeptidyl peptidase 4; Belongs to the peptidase S9B family.
     
 0.988
TMPRSS2
Transmembrane serine protease 2; Belongs to the peptidase S1 family.
    
 
 0.961
MME
Membrane metalloendopeptidase.
     
 0.959
SLC6A19
Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
   
 
 0.950
SLC6A20
Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
   
 
 0.940
AGT
SERPIN domain-containing protein; Belongs to the serpin family.
    
 0.939
PRCP
Prolylcarboxypeptidase.
     
 0.933
MEP1A
Meprin A subunit.
   
 
 0.921
XPNPEP2
X-prolyl aminopeptidase 2; Belongs to the peptidase M24B family.
   
 
 0.919
REN
Renin; Renin is a highly specific endopeptidase, whose only known function is to generate angiotensin I from angiotensinogen in the plasma, initiating a cascade of reactions that produce an elevation of blood pressure and increased sodium retention by the kidney.
      
 0.919
Your Current Organism:
Macaca fascicularis
NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.