Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ZNRF3Zinc and ring finger 3. (943 aa)    
Predicted Functional Partners:
RSPO3
R-spondin 3.
    
 0.965
RSPO1
R-spondin 1.
    
 0.963
RSPO2
Uncharacterized protein.
    
 0.955
FZD4
Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.
    
 0.943
FZD5
Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.
    
 0.938
FZD8
Frizzled class receptor 8; Belongs to the G-protein coupled receptor Fz/Smo family.
    
 0.931
FZD3
Frizzled-3; Belongs to the G-protein coupled receptor Fz/Smo family.
    
 0.930
FZD10
Frizzled class receptor 10; Belongs to the G-protein coupled receptor Fz/Smo family.
    
 0.924
FZD9
Frizzled class receptor 9; Belongs to the G-protein coupled receptor Fz/Smo family.
    
 0.924
FZD6
Frizzled class receptor 6; Belongs to the G-protein coupled receptor Fz/Smo family.
    
 0.923
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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