STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
UTS2Urotensin-2; Highly potent vasoconstrictor; Belongs to the urotensin-2 family. (125 aa)    
Predicted Functional Partners:
UTS2R
Urotensin-2 receptor; High affinity receptor for urotensin-2 and urotensin-2B. The activity of this receptor is mediated by a G-protein that activate a phosphatidylinositol-calcium second messenger system (By similarity).
   
 
 0.997
UTS2B
Urotensin 2B.
  
  
 0.983
EDN1
Preproendothelin-1.
   
 
 0.778
MCHR2
Melanin-concentrating hormone receptor 2; Receptor for melanin-concentrating hormone, coupled to G proteins that activate phosphoinositide hydrolysis.
   
 
 0.737
NMBR
Neuromedin B receptor; Belongs to the G-protein coupled receptor 1 family.
   
 
 0.658
TOR2A
Torsin.
   
  
 0.637
MCHR1
Melanin-concentrating hormone receptor 1; Receptor for melanin-concentrating hormone, coupled to both G proteins that inhibit adenylyl cyclase and G proteins that activate phosphoinositide hydrolysis.
   
 
 0.629
SSTR2
Somatostatin receptor 2; Belongs to the G-protein coupled receptor 1 family.
     
 0.607
SST
Somatostatin preproprotein.
   
  
 0.603
QRFP
Pyroglutamylated RFamide peptide.
     
 0.598
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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