LOC723314 protein (Macaca mulatta) - STRING interaction network

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

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[Homology]

Score

LOC723314

Uncharacterized protein. (1578 aa)

Predicted Functional Partners:

CD46

0.864

CD55

0.848

C1S

0.809

LOC722133

0.800

MASP2

0.749

CR1

0.740

CFI

0.738

CR2

0.690

C2

0.679

C5AR1

0.656

Your Current Organism:

Macaca mulatta

NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C1S	C2	ENSMMUP00000076188	ENSMMUP00000000987	Complement C1s; Belongs to the peptidase S1 family.	Uncharacterized protein; Belongs to the peptidase S1 family.	0.495
C1S	CD46	ENSMMUP00000076188	ENSMMUP00000009336	Complement C1s; Belongs to the peptidase S1 family.	Membrane cofactor protein; Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. May be involved in the fusion of the spermatozoa with the oocyte during fertilization.	0.630
C1S	CD55	ENSMMUP00000076188	ENSMMUP00000050092	Complement C1s; Belongs to the peptidase S1 family.	Uncharacterized protein.	0.654
C1S	LOC722133	ENSMMUP00000076188	ENSMMUP00000045849	Complement C1s; Belongs to the peptidase S1 family.	Uncharacterized protein; Belongs to the peptidase S1 family.	0.999
C1S	LOC723314	ENSMMUP00000076188	ENSMMUP00000001017	Complement C1s; Belongs to the peptidase S1 family.	Uncharacterized protein.	0.809
C1S	MASP2	ENSMMUP00000076188	ENSMMUP00000009783	Complement C1s; Belongs to the peptidase S1 family.	Mannan binding lectin serine peptidase 2; Belongs to the peptidase S1 family.	0.473
C2	C1S	ENSMMUP00000000987	ENSMMUP00000076188	Uncharacterized protein; Belongs to the peptidase S1 family.	Complement C1s; Belongs to the peptidase S1 family.	0.495
C2	CD46	ENSMMUP00000000987	ENSMMUP00000009336	Uncharacterized protein; Belongs to the peptidase S1 family.	Membrane cofactor protein; Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. May be involved in the fusion of the spermatozoa with the oocyte during fertilization.	0.610
C2	CD55	ENSMMUP00000000987	ENSMMUP00000050092	Uncharacterized protein; Belongs to the peptidase S1 family.	Uncharacterized protein.	0.563
C2	CFI	ENSMMUP00000000987	ENSMMUP00000027948	Uncharacterized protein; Belongs to the peptidase S1 family.	Uncharacterized protein.	0.866
C2	LOC722133	ENSMMUP00000000987	ENSMMUP00000045849	Uncharacterized protein; Belongs to the peptidase S1 family.	Uncharacterized protein; Belongs to the peptidase S1 family.	0.491
C2	LOC723314	ENSMMUP00000000987	ENSMMUP00000001017	Uncharacterized protein; Belongs to the peptidase S1 family.	Uncharacterized protein.	0.679
C2	MASP2	ENSMMUP00000000987	ENSMMUP00000009783	Uncharacterized protein; Belongs to the peptidase S1 family.	Mannan binding lectin serine peptidase 2; Belongs to the peptidase S1 family.	0.447
C5AR1	CD46	ENSMMUP00000064142	ENSMMUP00000009336	C5a anaphylatoxin chemotactic receptor 1; Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a. The ligand interacts with at least two sites on the receptor: a high-affinity site on the extracellular N-terminus, and a second site in the transmembrane region which activates downstream signaling events. Receptor activation stimulates chemotaxis, granule enzyme release, intracellular calcium release and superoxide anion production.	Membrane cofactor protein; Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. May be involved in the fusion of the spermatozoa with the oocyte during fertilization.	0.423
C5AR1	CD55	ENSMMUP00000064142	ENSMMUP00000050092	C5a anaphylatoxin chemotactic receptor 1; Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a. The ligand interacts with at least two sites on the receptor: a high-affinity site on the extracellular N-terminus, and a second site in the transmembrane region which activates downstream signaling events. Receptor activation stimulates chemotaxis, granule enzyme release, intracellular calcium release and superoxide anion production.	Uncharacterized protein.	0.481
C5AR1	LOC723314	ENSMMUP00000064142	ENSMMUP00000001017	C5a anaphylatoxin chemotactic receptor 1; Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a. The ligand interacts with at least two sites on the receptor: a high-affinity site on the extracellular N-terminus, and a second site in the transmembrane region which activates downstream signaling events. Receptor activation stimulates chemotaxis, granule enzyme release, intracellular calcium release and superoxide anion production.	Uncharacterized protein.	0.656
CD46	C1S	ENSMMUP00000009336	ENSMMUP00000076188	Membrane cofactor protein; Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. May be involved in the fusion of the spermatozoa with the oocyte during fertilization.	Complement C1s; Belongs to the peptidase S1 family.	0.630
CD46	C2	ENSMMUP00000009336	ENSMMUP00000000987	Membrane cofactor protein; Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. May be involved in the fusion of the spermatozoa with the oocyte during fertilization.	Uncharacterized protein; Belongs to the peptidase S1 family.	0.610
CD46	C5AR1	ENSMMUP00000009336	ENSMMUP00000064142	Membrane cofactor protein; Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. May be involved in the fusion of the spermatozoa with the oocyte during fertilization.	C5a anaphylatoxin chemotactic receptor 1; Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a. The ligand interacts with at least two sites on the receptor: a high-affinity site on the extracellular N-terminus, and a second site in the transmembrane region which activates downstream signaling events. Receptor activation stimulates chemotaxis, granule enzyme release, intracellular calcium release and superoxide anion production.	0.423
CD46	CD55	ENSMMUP00000009336	ENSMMUP00000050092	Membrane cofactor protein; Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. May be involved in the fusion of the spermatozoa with the oocyte during fertilization.	Uncharacterized protein.	0.650