Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
BAG3Uncharacterized protein. (575 aa)    
Predicted Functional Partners:
HSPB8
Heat shock protein beta-8; Displays temperature-dependent chaperone activity. Belongs to the small heat shock protein (HSP20) family.
   
 0.994
HSPA4
Heat shock protein family A (Hsp70) member 4.
   
 0.973
HSPA8
Heat shock cognate 71 kDa protein isoform 1; Belongs to the heat shock protein 70 family.
   
 0.897
LOC709412
Uncharacterized protein; Belongs to the heat shock protein 70 family.
   
 0.878
STUB1
STIP1 homology and U-box containing protein 1.
    
 0.871
HSPB1
Heat shock protein beta-1; Belongs to the small heat shock protein (HSP20) family.
   
 
 0.842
BAG1
BCL2 associated athanogene 1.
   
 0.833
SQSTM1
Sequestosome 1.
    
 
 0.825
CRYAB
Alpha-crystallin B chain; May contribute to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions.
   
 
 0.812
NBR1
NBR1 autophagy cargo receptor.
    
 
 0.801
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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