Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DBF4BDBF4 zinc finger B. (684 aa)    
Predicted Functional Partners:
CDC7
Cell division cycle 7-related protein kinase.
   
 0.934
DBF4
Protein DBF4 homolog A.
     
0.908
MCM4
DNA helicase; Belongs to the MCM family.
   
 0.849
MCM10
Minichromosome maintenance 10 replication initiation factor.
   
 0.829
MCM5
DNA helicase; Belongs to the MCM family.
   
 0.805
ORC2
Origin recognition complex subunit 2.
   
 0.805
MCM2
DNA helicase; Belongs to the MCM family.
   
 0.792
CDC45
Cell division cycle 45.
   
 0.788
MCM3
DNA helicase; Belongs to the MCM family.
   
 0.773
ATR
ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family.
    
 0.771
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.