Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-expression
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[Homology]
Score
COX17Cytochrome c oxidase copper chaperone. (63 aa)    
Predicted Functional Partners:
ATOX1
Copper transport protein ATOX1.
   
 
 0.941
COA5
Uncharacterized protein.
   
 
 0.936
COX19
Cytochrome c oxidase assembly protein COX19.
     
 0.933
COX11
Cytochrome c oxidase copper chaperone COX11.
   
 
 0.899
CCS
Copper chaperone for superoxide dismutase.
     
 0.896
CHCHD4
CHCH domain-containing protein.
   
 0.892
SCO1
SCO cytochrome c oxidase assembly protein 1.
   
 0.861
ENSMMUP00000074788
Uncharacterized protein.
   
 0.861
GFER
Sulfhydryl oxidase.
   
 0.838
COX5A
Cytochrome c oxidase subunit 5A, mitochondrial; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane [...]
   
 
 0.788
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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