STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ITGB2Integrin beta. (911 aa)    
Predicted Functional Partners:
ITGAL
Integrin subunit alpha L; Belongs to the integrin alpha chain family.
   
 0.999
ITGAM
Integrin subunit alpha M; Belongs to the integrin alpha chain family.
   
 0.998
ITGAX
Integrin subunit alpha X; Belongs to the integrin alpha chain family.
   
 0.998
ICAM1
Intercellular adhesion molecule 1; ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation (By similarity). Belongs to the immunoglobulin superfamily. ICAM family.
   
 0.989
ICAM2
ICAM_N domain-containing protein.
   
 
 0.976
JAM3
Junctional adhesion molecule 3.
   
 
 0.975
F11R
Junctional adhesion molecule A.
     
 0.970
C3
Uncharacterized protein.
   
 0.968
PTK2B
Protein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family.
   
 0.952
ITGB1
Integrin beta; Belongs to the integrin beta chain family.
  
 
0.951
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.