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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SDC2Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (201 aa)    
Predicted Functional Partners:
SDC4
Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family.
  
 
0.966
GPC1
Glypican 1; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family.
    
 0.958
SDC1
Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family.
  
 
0.953
FN1
Fibronectin isoform 1 preproprotein.
    
 0.925
RDX
Radixin.
    
 0.912
EZR
Ezrin.
    
 0.912
MSN
FERM domain-containing protein.
    
 0.912
HS2ST1
Heparan sulfate 2-O-sulfotransferase 1 isoform 1.
     
 0.698
PTK6
Tyrosine-protein kinase.
    
 
 0.690
CASK
Calcium/calmodulin dependent serine protein kinase; Belongs to the MAGUK family.
    
 0.677
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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