Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
TNKSPoly [ADP-ribose] polymerase. (1327 aa)    
Predicted Functional Partners:
RNF146
E3 ubiquitin-protein ligase RNF146 isoform b.
    
 0.975
GMDS
GDP-mannose 4,6 dehydratase isoform 1.
   
 
 0.966
TNKS2
Poly [ADP-ribose] polymerase.
   
  0.957
AXIN1
Axin 1.
    
 0.945
AXIN2
Axin 2.
    
 0.914
NEDD8
TERF1 interacting nuclear factor 2.
    
 0.908
BABAM1
BRISC and BRCA1-A complex member 1.
    
 0.844
USP25
Ubiquitin specific peptidase 25; Belongs to the peptidase C19 family.
    
 0.768
GLIS1
GLIS family zinc finger 1.
    
 0.748
NODAL
Nodal growth differentiation factor.
     
 0.736
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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