Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PKHD1L1PKHD1 like 1. (4245 aa)    
Predicted Functional Partners:
CDCP2
CUB domain containing protein 2.
    
 0.841
FAM111B
Family with sequence similarity 111 member B.
      
 0.768
CCDC73
Coiled-coil domain containing 73.
      
 0.726
CSMD3
CUB and Sushi multiple domains 3.
      
 0.712
SCLT1
Sodium channel and clathrin linker 1.
    
 0.671
SACS
Sacsin molecular chaperone.
      
 0.663
PRRT2
Proline-rich transmembrane protein 2 isoform 1.
      
 0.661
JPH4
Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels.
      
 0.661
PABPC3
Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family.
      
 0.601
ZDBF2
Zinc finger DBF-type containing 2.
      
 0.588
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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