Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
HELTUncharacterized protein. (327 aa)    
Predicted Functional Partners:
SATB1
DNA-binding protein SATB.
      
 0.585
ING2
Inhibitor of growth protein.
      
 0.536
SLC6A7
Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
      
 0.515
HRAS
Transforming protein p21.
    
 
 0.502
EMC8
ER membrane protein complex subunit 8.
      
 0.476
HES3
Hes family bHLH transcription factor 3.
      
 0.468
MNT
MAX network transcriptional repressor.
    
 
 0.467
MLX
MAX dimerization protein MLX.
      
 0.465
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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