P2RY12 protein (Macaca mulatta) - STRING interaction network

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Score

P2RY12

p2Y purinoceptor 12. (342 aa)

Predicted Functional Partners:

GNAI2

0.949

GNAI3

0.936

GNAI1

0.936

TMEM119

0.877

TREM2

0.814

P2RY13

0.812

CSF1R

0.802

CD68

0.753

CLEC7A

0.727

P2RX1

0.726

Your Current Organism:

Macaca mulatta

NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CD68	CLEC7A	ENSMMUP00000017747	ENSMMUP00000002925	CD68 molecule.	C-type lectin domain family 7 member A; Lectin that functions as pattern receptor specific for beta- 1,3-linked and beta-1,6-linked glucans, such as cell wall constituents from pathogenic bacteria and fungi. Induces phosphorylation of SCIMP after binding beta-glucans (By similarity). Necessary for the TLR2- mediated inflammatory response and for TLR2-mediated activation of NF- kappa-B. Enhances cytokine production in macrophages and dendritic cells. Mediates production of reactive oxygen species in the cell. Mediates phagocytosis of C.albicans conidia. Binds T-cells in a way that does [...]	0.607
CD68	CSF1R	ENSMMUP00000017747	ENSMMUP00000053422	CD68 molecule.	Colony stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	0.662
CD68	P2RY12	ENSMMUP00000017747	ENSMMUP00000001469	CD68 molecule.	p2Y purinoceptor 12.	0.753
CD68	TMEM119	ENSMMUP00000017747	ENSMMUP00000079763	CD68 molecule.	Uncharacterized protein.	0.580
CD68	TREM2	ENSMMUP00000017747	ENSMMUP00000033713	CD68 molecule.	Triggering receptor expressed on myeloid cells 2.	0.804
CLEC7A	CD68	ENSMMUP00000002925	ENSMMUP00000017747	C-type lectin domain family 7 member A; Lectin that functions as pattern receptor specific for beta- 1,3-linked and beta-1,6-linked glucans, such as cell wall constituents from pathogenic bacteria and fungi. Induces phosphorylation of SCIMP after binding beta-glucans (By similarity). Necessary for the TLR2- mediated inflammatory response and for TLR2-mediated activation of NF- kappa-B. Enhances cytokine production in macrophages and dendritic cells. Mediates production of reactive oxygen species in the cell. Mediates phagocytosis of C.albicans conidia. Binds T-cells in a way that does [...]	CD68 molecule.	0.607
CLEC7A	P2RY12	ENSMMUP00000002925	ENSMMUP00000001469	C-type lectin domain family 7 member A; Lectin that functions as pattern receptor specific for beta- 1,3-linked and beta-1,6-linked glucans, such as cell wall constituents from pathogenic bacteria and fungi. Induces phosphorylation of SCIMP after binding beta-glucans (By similarity). Necessary for the TLR2- mediated inflammatory response and for TLR2-mediated activation of NF- kappa-B. Enhances cytokine production in macrophages and dendritic cells. Mediates production of reactive oxygen species in the cell. Mediates phagocytosis of C.albicans conidia. Binds T-cells in a way that does [...]	p2Y purinoceptor 12.	0.727
CLEC7A	TMEM119	ENSMMUP00000002925	ENSMMUP00000079763	C-type lectin domain family 7 member A; Lectin that functions as pattern receptor specific for beta- 1,3-linked and beta-1,6-linked glucans, such as cell wall constituents from pathogenic bacteria and fungi. Induces phosphorylation of SCIMP after binding beta-glucans (By similarity). Necessary for the TLR2- mediated inflammatory response and for TLR2-mediated activation of NF- kappa-B. Enhances cytokine production in macrophages and dendritic cells. Mediates production of reactive oxygen species in the cell. Mediates phagocytosis of C.albicans conidia. Binds T-cells in a way that does [...]	Uncharacterized protein.	0.606
CLEC7A	TREM2	ENSMMUP00000002925	ENSMMUP00000033713	C-type lectin domain family 7 member A; Lectin that functions as pattern receptor specific for beta- 1,3-linked and beta-1,6-linked glucans, such as cell wall constituents from pathogenic bacteria and fungi. Induces phosphorylation of SCIMP after binding beta-glucans (By similarity). Necessary for the TLR2- mediated inflammatory response and for TLR2-mediated activation of NF- kappa-B. Enhances cytokine production in macrophages and dendritic cells. Mediates production of reactive oxygen species in the cell. Mediates phagocytosis of C.albicans conidia. Binds T-cells in a way that does [...]	Triggering receptor expressed on myeloid cells 2.	0.727
CSF1R	CD68	ENSMMUP00000053422	ENSMMUP00000017747	Colony stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	CD68 molecule.	0.662
CSF1R	P2RY12	ENSMMUP00000053422	ENSMMUP00000001469	Colony stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	p2Y purinoceptor 12.	0.802
CSF1R	P2RY13	ENSMMUP00000053422	ENSMMUP00000041932	Colony stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	Purinergic receptor P2Y13; Belongs to the G-protein coupled receptor 1 family.	0.413
CSF1R	TMEM119	ENSMMUP00000053422	ENSMMUP00000079763	Colony stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	Uncharacterized protein.	0.736
CSF1R	TREM2	ENSMMUP00000053422	ENSMMUP00000033713	Colony stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	Triggering receptor expressed on myeloid cells 2.	0.743
GNAI1	GNAI2	ENSMMUP00000030898	ENSMMUP00000026482	G protein subunit alpha i1.	Guanine nucleotide-binding protein G(I) subunit alpha-2 isoform 1.	0.968
GNAI1	GNAI3	ENSMMUP00000030898	ENSMMUP00000007669	G protein subunit alpha i1.	Guanine nucleotide-binding protein G(K) subunit alpha.	0.900
GNAI1	P2RY12	ENSMMUP00000030898	ENSMMUP00000001469	G protein subunit alpha i1.	p2Y purinoceptor 12.	0.936
GNAI2	GNAI1	ENSMMUP00000026482	ENSMMUP00000030898	Guanine nucleotide-binding protein G(I) subunit alpha-2 isoform 1.	G protein subunit alpha i1.	0.968
GNAI2	GNAI3	ENSMMUP00000026482	ENSMMUP00000007669	Guanine nucleotide-binding protein G(I) subunit alpha-2 isoform 1.	Guanine nucleotide-binding protein G(K) subunit alpha.	0.968
GNAI2	P2RY12	ENSMMUP00000026482	ENSMMUP00000001469	Guanine nucleotide-binding protein G(I) subunit alpha-2 isoform 1.	p2Y purinoceptor 12.	0.949