Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
PTPRTProtein tyrosine phosphatase receptor type T. (1460 aa)    
Predicted Functional Partners:
PTPN6
Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.
   
 0.692
RALGPS1
Ral GEF with PH domain and SH3 binding motif 1.
   
 0.668
SKAP2
Src kinase-associated phosphoprotein 2.
   
 
 0.661
ABLIM2
Actin binding LIM protein family member 2.
      
 0.602
PTPN14
Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class subfamily.
    
 
 0.549
PTPN3
Tyrosine-protein phosphatase non-receptor type; May act at junctions between the membrane and the cytoskeleton.
    
 
 0.538
CADPS
Uncharacterized protein.
   
  
 0.518
FRAS1
Fraser extracellular matrix complex subunit 1.
   
 0.517
ADCY2
Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
   
 
 0.511
PTPRJ
Protein tyrosine phosphatase receptor type J.
   
 
0.499
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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