Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TIMP4TIMP metallopeptidase inhibitor 4. (224 aa)    
Predicted Functional Partners:
MMP2
72 kDa type IV collagenase isoform a preproprotein.
    
 0.865
MMP9
Uncharacterized protein.
    
 0.801
MMP15
Matrix metallopeptidase 15.
   
 0.774
MMP3
Matrix metallopeptidase 3.
    
 0.756
MMP7
Matrix metallopeptidase 7.
    
 0.741
HPX
Hemopexin; Binds heme and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation.
    
 0.724
MMP24
Matrix metallopeptidase 24.
    
 0.714
MMP17
Matrix metallopeptidase 17.
    
 0.712
MMP8
Matrix metallopeptidase 8.
    
 0.711
MMP12
Matrix metallopeptidase 12.
    
 0.708
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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