Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
PDGFRLPlatelet derived growth factor receptor like. (375 aa)    
Predicted Functional Partners:
NRP2
Neuropilin; Belongs to the neuropilin family.
     
 0.730
PDGFB
Platelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family.
   
 0.677
ZNF550
Zinc finger protein 550.
    
 
 0.669
TUSC3
Tumor suppressor candidate 3 isoform a.
      
 0.668
GRB2
Growth factor receptor-bound protein 2 isoform 1.
   
 0.667
CHRNA6
Cholinergic receptor nicotinic alpha 6 subunit.
      
 0.645
GRIN3A
Glutamate ionotropic receptor NMDA type subunit 3A.
      
 0.633
SCRIB
Scribble planar cell polarity protein.
   
 0.628
RAMP1
Uncharacterized protein.
      
 0.623
PDGFRB
Platelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells.
   
 0.619
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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