POLN protein (Macaca mulatta) - STRING interaction network

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[Homology]

Score

POLN

DNA polymerase nu. (900 aa)

Predicted Functional Partners:

FANCD2

0.834

PCNA

0.816

HELQ

0.792

FEN1

0.717

BRCA2

0.685

FANCM

0.685

POLA1

0.680

FAN1

0.680

RAD50

0.671

NPL

0.670

Your Current Organism:

Macaca mulatta

NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BRCA2	FANCD2	ENSMMUP00000009432	ENSMMUP00000059729	BRCA2 DNA repair associated.	Uncharacterized protein.	0.998
BRCA2	FANCM	ENSMMUP00000009432	ENSMMUP00000021700	BRCA2 DNA repair associated.	FA complementation group M.	0.758
BRCA2	FEN1	ENSMMUP00000009432	ENSMMUP00000008754	BRCA2 DNA repair associated.	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	0.762
BRCA2	HELQ	ENSMMUP00000009432	ENSMMUP00000020129	BRCA2 DNA repair associated.	Helicase, POLQ like.	0.641
BRCA2	PCNA	ENSMMUP00000009432	ENSMMUP00000062455	BRCA2 DNA repair associated.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.765
BRCA2	POLA1	ENSMMUP00000009432	ENSMMUP00000042374	BRCA2 DNA repair associated.	DNA polymerase.	0.544
BRCA2	POLN	ENSMMUP00000009432	ENSMMUP00000001533	BRCA2 DNA repair associated.	DNA polymerase nu.	0.685
BRCA2	RAD50	ENSMMUP00000009432	ENSMMUP00000049353	BRCA2 DNA repair associated.	Zinc-hook domain-containing protein.	0.948
FAN1	FANCD2	ENSMMUP00000080679	ENSMMUP00000059729	Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family.	Uncharacterized protein.	0.997
FAN1	FANCM	ENSMMUP00000080679	ENSMMUP00000021700	Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family.	FA complementation group M.	0.870
FAN1	HELQ	ENSMMUP00000080679	ENSMMUP00000020129	Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family.	Helicase, POLQ like.	0.534
FAN1	PCNA	ENSMMUP00000080679	ENSMMUP00000062455	Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.759
FAN1	POLN	ENSMMUP00000080679	ENSMMUP00000001533	Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family.	DNA polymerase nu.	0.680
FANCD2	BRCA2	ENSMMUP00000059729	ENSMMUP00000009432	Uncharacterized protein.	BRCA2 DNA repair associated.	0.998
FANCD2	FAN1	ENSMMUP00000059729	ENSMMUP00000080679	Uncharacterized protein.	Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family.	0.997
FANCD2	FANCM	ENSMMUP00000059729	ENSMMUP00000021700	Uncharacterized protein.	FA complementation group M.	0.998
FANCD2	FEN1	ENSMMUP00000059729	ENSMMUP00000008754	Uncharacterized protein.	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	0.604
FANCD2	HELQ	ENSMMUP00000059729	ENSMMUP00000020129	Uncharacterized protein.	Helicase, POLQ like.	0.904
FANCD2	PCNA	ENSMMUP00000059729	ENSMMUP00000062455	Uncharacterized protein.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.848
FANCD2	POLN	ENSMMUP00000059729	ENSMMUP00000001533	Uncharacterized protein.	DNA polymerase nu.	0.834