Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ZFYVE28Zinc finger FYVE-type containing 28. (942 aa)    
Predicted Functional Partners:
RPTOR
Regulatory associated protein of MTOR complex 1.
    
   0.704
RBM46
RNA binding motif protein 46.
      
 0.673
EXD3
Exonuclease 3'-5' domain containing 3.
      
 0.668
MLST8
MTOR associated protein, LST8 homolog.
    
   0.526
MTOR
Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family.
    
   0.526
PAX8
Paired box 8.
      
 0.523
CHMP3
E3 ubiquitin-protein ligase RNF103 isoform 1.
      
 0.520
ENSMMUP00000064305
Uncharacterized protein.
      
 0.508
C1H1orf112
Chromosome 1 C1orf112 homolog.
      
 0.477
GPT2
Glutamic--pyruvic transaminase 2.
      
 0.452
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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