Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ARHGEF25Rho guanine nucleotide exchange factor 25. (619 aa)    
Predicted Functional Partners:
RHOA
Ras homolog family member A.
   
 0.816
STK17B
Serine/threonine-protein kinase 17B; Belongs to the protein kinase superfamily.
 
   
  0.795
GNAQ
Guanine nucleotide-binding protein G(Q) subunit alpha.
    
 0.754
CDC42
Cell division control protein 42 homolog isoform 1.
    
 0.615
RHOG
Rho-related GTP-binding protein RhoG.
    
 0.558
GNA11
Guanine nucleotide-binding protein subunit alpha-11.
    
 0.554
GNA14
G protein subunit alpha 14.
    
 0.554
SLC26A10
Solute carrier family 26 member 10.
   
  
 0.534
RND3
Rho-related GTP-binding protein RhoE.
   
 0.528
RND1
Rho-related GTP-binding protein Rho6.
   
 0.528
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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