Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MAPK15Mitogen-activated protein kinase. (544 aa)    
Predicted Functional Partners:
JUN
Transcription factor AP-1; Belongs to the bZIP family.
    
 0.827
FOS
V-fos FBJ murine osteosarcoma viral oncogene-like protein.
    
 0.804
FOSB
BZIP domain-containing protein.
    
 0.795
FOSL1
FOS like 1, AP-1 transcription factor subunit.
    
 0.779
JUND
JunD proto-oncogene, AP-1 transcription factor subunit.
    
 0.759
RFX2
Regulatory factor X2.
   
  
 0.709
ABCG4
ATP binding cassette subfamily G member 4.
    
 
 0.704
CLIC3
Chloride intracellular channel protein; Belongs to the chloride channel CLIC family.
    
 
 0.682
PRND
Prion like protein doppel.
   
  
 0.671
ALOX5AP
Arachidonate 5-lipoxygenase-activating protein; Required for leukotriene biosynthesis by ALOX5 (5- lipoxygenase). Anchors ALOX5 to the membrane. Binds arachidonic acid, and could play an essential role in the transfer of arachidonic acid to ALOX5. Binds to MK-886, a compound that blocks the biosynthesis of leukotrienes (By similarity); Belongs to the MAPEG family.
      
 0.667
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
Server load: low (38%) [HD]