Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
SPINK14Serine peptidase inhibitor, Kazal type 14 (putative). (97 aa)    
Predicted Functional Partners:
DSTYK
Dual serine/threonine and tyrosine protein kinase; Acts as a positive regulator of ERK phosphorylation downstream of fibroblast growth factor-receptor activation. Involved in the regulation of both caspase-dependent apoptosis and caspase- independent cell death. In the skin, it plays a predominant role in suppressing caspase-dependent apoptosis in response to UV stress in a range of dermal cell types.
    
 
 0.841
KCNMB3
Potassium calcium-activated channel subfamily M regulatory beta subunit 3.
      
 0.840
SPINK6
Serine peptidase inhibitor, Kazal type 6.
      
 0.807
CTRB2
Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.
    
 0.784
FAM92B
Family with sequence similarity 92 member B.
      
 0.768
MUSTN1
Uncharacterized protein.
    
 
 0.766
SIX6
SIX homeobox 6.
      
 0.693
RHOH
Rho-related GTP-binding protein RhoH.
      
 0.689
ST6GAL2
ST6 beta-galactoside alpha-2,6-sialyltransferase 2; Belongs to the glycosyltransferase 29 family.
      
 0.684
DLX4
Distal-less homeobox 4.
      
 0.663
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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