Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
SETD3Protein-histidine N-methyltransferase. (595 aa)    
Predicted Functional Partners:
ACTG2
Actin gamma 2, smooth muscle.
    
 
 0.708
SMYD3
SET and MYND domain-containing protein 3 isoform 1.
     
 0.676
SETD7
Uncharacterized protein.
   
 
 0.668
NSD3
Nuclear receptor binding SET domain protein 3.
     
 0.632
ACTA1
Actin alpha 1, skeletal muscle.
    
 
 0.615
LOC721299
Uncharacterized protein; Belongs to the actin family.
    
 
 0.615
LOC700393
ANK_REP_REGION domain-containing protein; Belongs to the actin family.
    
 
 0.614
NMD3
60S ribosomal export protein NMD3; Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit; Belongs to the NMD3 family.
   
  
 0.581
LOC705671
Uncharacterized protein.
    
 
 0.571
ACTG1
Actin, cytoplasmic 2.
    
 
 0.571
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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