Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
GPR150G protein-coupled receptor 150. (435 aa)    
Predicted Functional Partners:
AVP
Arginine vasopressin; Belongs to the vasopressin/oxytocin family.
   
 0.759
OXT
Oxytocin/neurophysin I prepropeptide; Belongs to the vasopressin/oxytocin family.
   
 0.642
PRLR
Prolactin receptor; This is a receptor for the anterior pituitary hormone prolactin.
      
 0.555
PGR
Uncharacterized protein.
   
 
 0.550
IGFBP1
Uncharacterized protein.
      
 0.523
EGF
Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.
     
 0.519
LEPR
Leptin receptor; Receptor for hormone LEP/leptin (By similarity). On ligand binding, mediates LEP central and peripheral effects through the activation of different signaling pathways such as JAK2/STAT3 and MAPK cascade/FOS. In the hypothalamus, LEP acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo-pituitary-adrenal hormones. In the periphery, increases basal metabolism, influences reproductiv [...]
    
 
 0.516
NPS
Neuropeptide S.
     
 0.515
EDN1
Preproendothelin-1.
    
 0.510
RXFP2
G_PROTEIN_RECEP_F1_2 domain-containing protein.
     
 0.498
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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