Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LLGL2LLGL scribble cell polarity complex component 2. (1020 aa)    
Predicted Functional Partners:
PRKCZ
Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
    
 0.992
PRKCI
Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
    
 0.992
LLGL1
LLGL scribble cell polarity complex component 1.
  
 
 
0.974
DLG4
Uncharacterized protein; Belongs to the MAGUK family.
   
 0.950
DLG1
Disks large homolog 1 isoform 2; Belongs to the MAGUK family.
   
 0.946
PARD6B
Partitioning defective 6 homolog beta.
    
 
 0.924
PARD6A
Par-6 family cell polarity regulator alpha.
    
 
 0.924
UBE3A
Ubiquitin-protein ligase E3A; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates.
     
 0.923
DLG3
Uncharacterized protein; Belongs to the MAGUK family.
   
 0.892
DLG2
Discs large MAGUK scaffold protein 2.
   
 0.889
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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