Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
GIMAP5AIG1-type G domain-containing protein. (338 aa)    
Predicted Functional Partners:
GIMAP4
GTPase, IMAP family member 4.
  
  
0.648
ZNF83
Zinc finger protein 83.
    
 0.624
PCGF2
Polycomb group RING finger protein 2.
    
 0.614
UNC79
Unc-79 homolog, NALCN channel complex subunit.
    
 0.568
GIMAP6
GTPase, IMAP family member 6.
  
  
0.546
ASIP
Agouti-signaling protein; Involved in the regulation of melanogenesis. The binding of ASP to MC1R precludes alpha-MSH initiated signaling and thus blocks production of cAMP, leading to a down-regulation of eumelanogenesis (brown/black pigment) and thus increasing synthesis of pheomelanin (yellow/red pigment) (By similarity).
      
 0.518
PNMA1
Paraneoplastic antigen Ma1.
    
 0.505
ZNF775
Uncharacterized protein.
    
 0.501
ITK
Tyrosine-protein kinase.
   
 0.499
ZFHX4
Zinc finger homeobox 4.
      
 0.485
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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