Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ASB13Ankyrin repeat and SOCS box containing 13. (460 aa)    
Predicted Functional Partners:
CUL5
Cullin 5; Belongs to the cullin family.
    
 0.827
LRRC41
Leucine-rich repeat-containing protein 41.
     
 0.643
ELOC
Elongin C; Belongs to the SKP1 family.
    
 0.600
RNF7
RING-box protein 2 isoform 1.
    
 0.597
PSMD2
26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family.
    
 0.586
PSMB10
Proteasome subunit beta.
    
 0.534
ASB6
Ankyrin repeat and SOCS box containing 6.
    
 0.529
PSMD8
CSN8_PSD8_EIF3K domain-containing protein.
    
 0.528
ANKRD46
Ankyrin repeat domain 46.
  
 
  0.523
KLHL42
Kelch domain-containing protein 5.
     
 0.520
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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