Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
FARP2FERM, ARH/RhoGEF and pleckstrin domain protein 2. (1055 aa)    
Predicted Functional Partners:
CDC42
Cell division control protein 42 homolog isoform 1.
     
 0.930
PIP5K1C
Phosphatidylinositol-4-phosphate 5-kinase type 1 gamma.
     
 0.926
SRC
Tyrosine-protein kinase.
    
  0.921
RAP1B
Ras-related protein Rap-1b isoform 1.
     
 0.914
RAP1A
RAP1A, member of RAS oncogene family.
     
 0.914
NRP1
Neuropilin; Belongs to the neuropilin family.
     
 0.783
PLXNA4
Plexin A4.
     
 0.729
RND1
Rho-related GTP-binding protein Rho6.
     
 0.687
SEMA3A
Semaphorin 3A; Belongs to the semaphorin family.
     
 0.613
ITSN2
Intersectin 2.
     
 0.604
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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