Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ASCL2Achaete-scute family bHLH transcription factor 2. (193 aa)    
Predicted Functional Partners:
TCF3
Transcription factor 3.
   
 0.786
TCF12
Transcription factor 12 isoform a.
   
 0.731
TCF4
Transcription factor 4.
   
 0.679
CPA4
Carboxypeptidase A4.
   
  
 0.678
PHLDA2
Pleckstrin homology like domain family A member 2.
      
 0.676
NDRG1
N-myc downstream regulated 1.
      
 0.636
LGR5
Leucine rich repeat containing G protein-coupled receptor 5.
      
 0.628
TSSC4
Uncharacterized protein.
      
 0.625
RABEP2
Rabaptin, RAB GTPase binding effector protein 2.
      
 0.598
HES4
Hes family bHLH transcription factor 4.
   
 0.592
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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