Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
UBE2L6Ubiquitin conjugating enzyme E2 L6; Belongs to the ubiquitin-conjugating enzyme family. (152 aa)    
Predicted Functional Partners:
ISG15
Ubiquitin-like protein ISG15.
   
 0.994
PRKN
E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily.
    
 0.983
UBA7
Ubiquitin like modifier activating enzyme 7; Belongs to the ubiquitin-activating E1 family.
  
 0.982
UBB
Uncharacterized protein.
   
 0.981
UBA52
Ubiquitin-60S ribosomal protein L40.
    
 0.979
UBC
Uncharacterized protein.
   
 0.966
RPS27A-2
Ubiquitin-40S ribosomal protein S27a.
    
 0.960
UBA1
Ubiquitin like modifier activating enzyme 1; Belongs to the ubiquitin-activating E1 family.
  
 0.894
ARIH1
RBR-type E3 ubiquitin transferase.
   
 0.887
IFI35
Interferon induced protein 35.
   
 
 0.877
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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