Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TNFAIP8L3Uncharacterized protein. (292 aa)    
Predicted Functional Partners:
SUSD6
Sushi domain-containing protein.
      
 0.900
ANKRD9
Ankyrin repeat domain 9.
      
 0.878
VSTM2B
V-set and transmembrane domain containing 2B.
      
 0.665
AP4E1
AP-4 complex subunit epsilon; Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin- associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system.
      
 0.640
TNFRSF21
Tumor necrosis factor receptor superfamily member 21.
      
 0.525
LMCD1
LIM and cysteine-rich domains protein 1.
    
 
 0.519
LYSMD2
Uncharacterized protein.
      
 0.517
COG6
Conserved oligomeric Golgi complex subunit 6; Required for normal Golgi function.
      
 0.490
ELMOD1
ELMO domain-containing protein 1 isoform 1.
      
 0.489
FAM174B
Family with sequence similarity 174 member B.
      
 0.483
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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