Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
IRX3Iroquois homeobox 3. (501 aa)    
Predicted Functional Partners:
IRX5
Iroquois homeobox 5.
  
  
0.906
FTO
FTO alpha-ketoglutarate dependent dioxygenase.
      
 0.825
SCUBE2
Signal peptide, CUB domain and EGF like domain containing 2.
    
 
 0.773
DBX2
Developing brain homeobox 2.
    
 
 0.670
GPR84
Inflammation-related G-protein coupled receptor EX33.
      
 0.667
SALL4
Spalt like transcription factor 4.
      
 0.658
ARID4B
AT-rich interaction domain 4B.
    
 
 0.640
IRX2
Iroquois homeobox 2.
   
  
 0.621
CNPY1
Canopy FGF signaling regulator 1.
      
 0.619
TET2
Tet methylcytosine dioxygenase 2.
    
 
 0.597
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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