STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIO1Iodothyronine deiodinase; Responsible for the deiodination of T4 (3,5,3',5'- tetraiodothyronine). (248 aa)    
Predicted Functional Partners:
DIO2
Iodothyronine deiodinase; Responsible for the deiodination of T4 (3,5,3',5'- tetraiodothyronine).
     
 0.973
THRA
Thyroid hormone receptor alpha.
   
  
 0.721
ACAA2
3-ketoacyl-CoA thiolase, mitochondrial; Belongs to the thiolase-like superfamily. Thiolase family.
      
 0.651
SELENOO
Selenoprotein O.
      
 0.651
LOC106995978
Epidermal-type fatty acid-binding protein; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
   
  
 0.616
TXNRD2
Uncharacterized protein.
   
  
 0.509
TXNRD3
Thioredoxin reductase 3.
      
 0.506
TXNRD1
Thioredoxin reductase 1; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
      
 0.499
THRB
Thyroid hormone receptor beta.
   
  
 0.468
GLRX
Glutaredoxin-1.
      
 0.445
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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