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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PDAP1PP28 domain-containing protein. (191 aa)    
Predicted Functional Partners:
CAPZA2
F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
      
 0.843
RCN2
Reticulocalbin 2.
      
 0.824
CDC42EP4
Cdc42 effector protein 4.
      
 0.780
OGDH
Oxoglutarate dehydrogenase.
      
 0.686
STMN3
Stathmin; Belongs to the stathmin family.
      
 0.599
PPT1
Uncharacterized protein.
      
 0.595
SLC7A5
Large neutral amino acids transporter small subunit 1.
      
 0.592
ROCK2
Uncharacterized protein; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.
      
 0.530
CSNK2B
Chimera Csnk2b-Ly6g5b splicing isoform 992.
   
  
 0.515
PDGFA
Platelet derived growth factor subunit A; Belongs to the PDGF/VEGF growth factor family.
    
 
 0.506
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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