Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
KRT25Keratin 25; Belongs to the intermediate filament family. (450 aa)    
Predicted Functional Partners:
KRT27
Keratin 27; Belongs to the intermediate filament family.
   
  0.938
KRT28
Keratin 28; Belongs to the intermediate filament family.
   
 
  0.909
KRT26
Keratin 26; Belongs to the intermediate filament family.
   
 
  0.905
KRT71
Keratin 71; Belongs to the intermediate filament family.
  
0.853
DSG4
Desmoglein 4; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
  
  
 0.649
KRT24
Keratin 24; Belongs to the intermediate filament family.
   
 
  0.628
KRT82
Keratin 82; Belongs to the intermediate filament family.
  
0.624
KRT37
Keratin 37; Belongs to the intermediate filament family.
   
  0.621
TCHH
Trichohyalin.
   
 0.615
KRTCAP3
Keratinocyte associated protein 3.
      
 0.610
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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