Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
KRT12Keratin 12; Belongs to the intermediate filament family. (495 aa)    
Predicted Functional Partners:
KRT19
Keratin, type I cytoskeletal 19; Belongs to the intermediate filament family.
   
  0.849
KRT16
Keratin 16; Belongs to the intermediate filament family.
   
 
  0.847
KRT13
IF rod domain-containing protein; Belongs to the intermediate filament family.
   
 
  0.830
KRT38
Keratin 38; Belongs to the intermediate filament family.
   
  0.809
KERA
Keratocan.
    
 0.707
KRT37
Keratin 37; Belongs to the intermediate filament family.
   
  0.621
CHST6
Sulfotransferase; Belongs to the sulfotransferase 1 family.
      
 0.602
UBIAD1
UbiA prenyltransferase domain-containing protein 1.
      
 0.602
PAX6
Uncharacterized protein.
    
 
 0.590
KRT33B
Keratin 33B; Belongs to the intermediate filament family.
   
 
  0.578
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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