Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
BRD8Bromodomain containing 8. (1235 aa)    
Predicted Functional Partners:
EP400
E1A binding protein p400.
    
 0.998
DMAP1
DNA methyltransferase 1 associated protein 1.
    
 0.998
RUVBL1
RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding.
    
 0.997
MRGBP
MRG domain binding protein.
    
 0.997
KAT5
Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family.
   
 0.996
ING3
Inhibitor of growth protein.
    
 0.996
MEAF6
MYST/Esa1 associated factor 6.
    
 0.991
ACTL6A
Actin-like protein 6A isoform 1; Belongs to the actin family.
   
 0.990
MORF4L1
MRG domain-containing protein.
    
 0.983
MORF4L2
Mortality factor 4 like 2.
    
 0.983
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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