Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
KRT39Keratin 39; Belongs to the intermediate filament family. (491 aa)    
Predicted Functional Partners:
KRT86
Type II hair keratin Hb6; Belongs to the intermediate filament family.
    
 0.723
PPL
Periplakin.
    
 
 0.652
KRT81
Keratin 81; Belongs to the intermediate filament family.
  
0.638
PPP1CC
Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family.
      
 0.635
KRT82
Keratin 82; Belongs to the intermediate filament family.
  
  
0.569
PPP1CB
Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family.
      
 0.561
KRT85
Keratin 85; Belongs to the intermediate filament family.
   
 
0.551
KRT84
Keratin 84; Belongs to the intermediate filament family.
  
 
0.550
KRTCAP3
Keratinocyte associated protein 3.
      
 0.520
KRT80
Keratin 80; Belongs to the intermediate filament family.
     
0.519
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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