KIR3DL3 protein (Macaca mulatta) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

KIR3DL3

Uncharacterized protein. (475 aa)

Predicted Functional Partners:

HLA-E

0.973

LOC720132

0.928

PTPN11

0.922

MAMU-F

0.919

PTPN6

0.919

TYROBP

0.670

KLRD1

0.648

KLRC2

0.586

NCR2

0.523

B2M

0.469

Your Current Organism:

Macaca mulatta

NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
B2M	HLA-E	ENSMMUP00000075968	ENSMMUP00000041996	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity).	Major histocompatibility complex, class I, E; Belongs to the MHC class I family.	0.990
B2M	KIR3DL3	ENSMMUP00000075968	ENSMMUP00000002017	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity).	Uncharacterized protein.	0.469
B2M	KLRD1	ENSMMUP00000075968	ENSMMUP00000024061	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity).	Natural killer cells antigen CD94; Plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells.	0.759
B2M	LOC720132	ENSMMUP00000075968	ENSMMUP00000064805	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity).	Major histocompatibility complex, class I, AG; Belongs to the MHC class I family.	0.973
B2M	MAMU-F	ENSMMUP00000075968	ENSMMUP00000011541	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity).	Mamu class I histocompatibility antigen, alpha chain F; Involved in the presentation of foreign antigens to the immune system.	0.974
B2M	TYROBP	ENSMMUP00000075968	ENSMMUP00000074812	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity).	TYRO protein tyrosine kinase-binding protein; Adapter protein which non-covalently associates with activating receptors found on the surface of a variety of immune cells to mediate signaling and cell activation following ligand binding by the receptors (By similarity). TYROBP is tyrosine-phosphorylated in the ITAM domain following ligand binding by the associated receptors which leads to activation of additional tyrosine kinases and subsequent cell activation (By similarity). Also has an inhibitory role in some cells (By similarity). Non-covalently associates with activating receptors [...]	0.489
HLA-E	B2M	ENSMMUP00000041996	ENSMMUP00000075968	Major histocompatibility complex, class I, E; Belongs to the MHC class I family.	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity).	0.990
HLA-E	KIR3DL3	ENSMMUP00000041996	ENSMMUP00000002017	Major histocompatibility complex, class I, E; Belongs to the MHC class I family.	Uncharacterized protein.	0.973
HLA-E	KLRC2	ENSMMUP00000041996	ENSMMUP00000050583	Major histocompatibility complex, class I, E; Belongs to the MHC class I family.	NKG2-C type II integral membrane protein; Plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells.	0.993
HLA-E	KLRD1	ENSMMUP00000041996	ENSMMUP00000024061	Major histocompatibility complex, class I, E; Belongs to the MHC class I family.	Natural killer cells antigen CD94; Plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells.	0.999
HLA-E	LOC720132	ENSMMUP00000041996	ENSMMUP00000064805	Major histocompatibility complex, class I, E; Belongs to the MHC class I family.	Major histocompatibility complex, class I, AG; Belongs to the MHC class I family.	0.903
HLA-E	MAMU-F	ENSMMUP00000041996	ENSMMUP00000011541	Major histocompatibility complex, class I, E; Belongs to the MHC class I family.	Mamu class I histocompatibility antigen, alpha chain F; Involved in the presentation of foreign antigens to the immune system.	0.908
HLA-E	TYROBP	ENSMMUP00000041996	ENSMMUP00000074812	Major histocompatibility complex, class I, E; Belongs to the MHC class I family.	TYRO protein tyrosine kinase-binding protein; Adapter protein which non-covalently associates with activating receptors found on the surface of a variety of immune cells to mediate signaling and cell activation following ligand binding by the receptors (By similarity). TYROBP is tyrosine-phosphorylated in the ITAM domain following ligand binding by the associated receptors which leads to activation of additional tyrosine kinases and subsequent cell activation (By similarity). Also has an inhibitory role in some cells (By similarity). Non-covalently associates with activating receptors [...]	0.656
KIR3DL3	B2M	ENSMMUP00000002017	ENSMMUP00000075968	Uncharacterized protein.	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity).	0.469
KIR3DL3	HLA-E	ENSMMUP00000002017	ENSMMUP00000041996	Uncharacterized protein.	Major histocompatibility complex, class I, E; Belongs to the MHC class I family.	0.973
KIR3DL3	KLRC2	ENSMMUP00000002017	ENSMMUP00000050583	Uncharacterized protein.	NKG2-C type II integral membrane protein; Plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells.	0.586
KIR3DL3	KLRD1	ENSMMUP00000002017	ENSMMUP00000024061	Uncharacterized protein.	Natural killer cells antigen CD94; Plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells.	0.648
KIR3DL3	LOC720132	ENSMMUP00000002017	ENSMMUP00000064805	Uncharacterized protein.	Major histocompatibility complex, class I, AG; Belongs to the MHC class I family.	0.928
KIR3DL3	MAMU-F	ENSMMUP00000002017	ENSMMUP00000011541	Uncharacterized protein.	Mamu class I histocompatibility antigen, alpha chain F; Involved in the presentation of foreign antigens to the immune system.	0.919
KIR3DL3	NCR2	ENSMMUP00000002017	ENSMMUP00000004900	Uncharacterized protein.	Natural cytotoxicity triggering receptor 2.	0.523