GZMA protein (Macaca mulatta) - STRING interaction network

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[Homology]

Score

GZMA

Granzyme A; Belongs to the peptidase S1 family. (262 aa)

Predicted Functional Partners:

PRF1

0.956

GNLY

0.953

NKG7

0.941

CD8A

0.921

GZMK

0.915

CCL5

0.904

CD3D

0.903

KLRB1

0.865

GZMB

0.864

CD247

0.861

Your Current Organism:

Macaca mulatta

NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CCL5	CD247	ENSMMUP00000073204	ENSMMUP00000059589	C-C motif chemokine 5; Chemoattractant for blood monocytes, memory T-helper cells and eosinophils. Causes the release of histamine from basophils and activates eosinophils. May activate several chemokine receptors including CCR1, CCR3, CCR4 and CCR5. May also be an agonist of the G protein-coupled receptor GPR75. Together with GPR75, may play a role in neuron survival through activation of a downstream signaling pathway involving the PI3, Akt and MAP kinases. By activating GPR75 may also play a role in insulin secretion by islet cells. Belongs to the intercrine beta (chemokine CC) family.	CD247 molecule.	0.413
CCL5	CD3D	ENSMMUP00000073204	ENSMMUP00000023161	C-C motif chemokine 5; Chemoattractant for blood monocytes, memory T-helper cells and eosinophils. Causes the release of histamine from basophils and activates eosinophils. May activate several chemokine receptors including CCR1, CCR3, CCR4 and CCR5. May also be an agonist of the G protein-coupled receptor GPR75. Together with GPR75, may play a role in neuron survival through activation of a downstream signaling pathway involving the PI3, Akt and MAP kinases. By activating GPR75 may also play a role in insulin secretion by islet cells. Belongs to the intercrine beta (chemokine CC) family.	Ig_4 domain-containing protein.	0.450
CCL5	CD8A	ENSMMUP00000073204	ENSMMUP00000004695	C-C motif chemokine 5; Chemoattractant for blood monocytes, memory T-helper cells and eosinophils. Causes the release of histamine from basophils and activates eosinophils. May activate several chemokine receptors including CCR1, CCR3, CCR4 and CCR5. May also be an agonist of the G protein-coupled receptor GPR75. Together with GPR75, may play a role in neuron survival through activation of a downstream signaling pathway involving the PI3, Akt and MAP kinases. By activating GPR75 may also play a role in insulin secretion by islet cells. Belongs to the intercrine beta (chemokine CC) family.	CD8a molecule.	0.881
CCL5	GNLY	ENSMMUP00000073204	ENSMMUP00000079706	C-C motif chemokine 5; Chemoattractant for blood monocytes, memory T-helper cells and eosinophils. Causes the release of histamine from basophils and activates eosinophils. May activate several chemokine receptors including CCR1, CCR3, CCR4 and CCR5. May also be an agonist of the G protein-coupled receptor GPR75. Together with GPR75, may play a role in neuron survival through activation of a downstream signaling pathway involving the PI3, Akt and MAP kinases. By activating GPR75 may also play a role in insulin secretion by islet cells. Belongs to the intercrine beta (chemokine CC) family.	Uncharacterized protein.	0.727
CCL5	GZMA	ENSMMUP00000073204	ENSMMUP00000002136	C-C motif chemokine 5; Chemoattractant for blood monocytes, memory T-helper cells and eosinophils. Causes the release of histamine from basophils and activates eosinophils. May activate several chemokine receptors including CCR1, CCR3, CCR4 and CCR5. May also be an agonist of the G protein-coupled receptor GPR75. Together with GPR75, may play a role in neuron survival through activation of a downstream signaling pathway involving the PI3, Akt and MAP kinases. By activating GPR75 may also play a role in insulin secretion by islet cells. Belongs to the intercrine beta (chemokine CC) family.	Granzyme A; Belongs to the peptidase S1 family.	0.904
CCL5	GZMB	ENSMMUP00000073204	ENSMMUP00000018888	C-C motif chemokine 5; Chemoattractant for blood monocytes, memory T-helper cells and eosinophils. Causes the release of histamine from basophils and activates eosinophils. May activate several chemokine receptors including CCR1, CCR3, CCR4 and CCR5. May also be an agonist of the G protein-coupled receptor GPR75. Together with GPR75, may play a role in neuron survival through activation of a downstream signaling pathway involving the PI3, Akt and MAP kinases. By activating GPR75 may also play a role in insulin secretion by islet cells. Belongs to the intercrine beta (chemokine CC) family.	Granzyme B; Belongs to the peptidase S1 family.	0.741
CCL5	GZMK	ENSMMUP00000073204	ENSMMUP00000026561	C-C motif chemokine 5; Chemoattractant for blood monocytes, memory T-helper cells and eosinophils. Causes the release of histamine from basophils and activates eosinophils. May activate several chemokine receptors including CCR1, CCR3, CCR4 and CCR5. May also be an agonist of the G protein-coupled receptor GPR75. Together with GPR75, may play a role in neuron survival through activation of a downstream signaling pathway involving the PI3, Akt and MAP kinases. By activating GPR75 may also play a role in insulin secretion by islet cells. Belongs to the intercrine beta (chemokine CC) family.	Granzyme K; Belongs to the peptidase S1 family.	0.682
CCL5	KLRB1	ENSMMUP00000073204	ENSMMUP00000054695	C-C motif chemokine 5; Chemoattractant for blood monocytes, memory T-helper cells and eosinophils. Causes the release of histamine from basophils and activates eosinophils. May activate several chemokine receptors including CCR1, CCR3, CCR4 and CCR5. May also be an agonist of the G protein-coupled receptor GPR75. Together with GPR75, may play a role in neuron survival through activation of a downstream signaling pathway involving the PI3, Akt and MAP kinases. By activating GPR75 may also play a role in insulin secretion by islet cells. Belongs to the intercrine beta (chemokine CC) family.	Killer cell lectin like receptor B1.	0.413
CCL5	NKG7	ENSMMUP00000073204	ENSMMUP00000031485	C-C motif chemokine 5; Chemoattractant for blood monocytes, memory T-helper cells and eosinophils. Causes the release of histamine from basophils and activates eosinophils. May activate several chemokine receptors including CCR1, CCR3, CCR4 and CCR5. May also be an agonist of the G protein-coupled receptor GPR75. Together with GPR75, may play a role in neuron survival through activation of a downstream signaling pathway involving the PI3, Akt and MAP kinases. By activating GPR75 may also play a role in insulin secretion by islet cells. Belongs to the intercrine beta (chemokine CC) family.	Natural killer cell granule protein 7.	0.893
CCL5	PRF1	ENSMMUP00000073204	ENSMMUP00000070226	C-C motif chemokine 5; Chemoattractant for blood monocytes, memory T-helper cells and eosinophils. Causes the release of histamine from basophils and activates eosinophils. May activate several chemokine receptors including CCR1, CCR3, CCR4 and CCR5. May also be an agonist of the G protein-coupled receptor GPR75. Together with GPR75, may play a role in neuron survival through activation of a downstream signaling pathway involving the PI3, Akt and MAP kinases. By activating GPR75 may also play a role in insulin secretion by islet cells. Belongs to the intercrine beta (chemokine CC) family.	Perforin 1.	0.697
CD247	CCL5	ENSMMUP00000059589	ENSMMUP00000073204	CD247 molecule.	C-C motif chemokine 5; Chemoattractant for blood monocytes, memory T-helper cells and eosinophils. Causes the release of histamine from basophils and activates eosinophils. May activate several chemokine receptors including CCR1, CCR3, CCR4 and CCR5. May also be an agonist of the G protein-coupled receptor GPR75. Together with GPR75, may play a role in neuron survival through activation of a downstream signaling pathway involving the PI3, Akt and MAP kinases. By activating GPR75 may also play a role in insulin secretion by islet cells. Belongs to the intercrine beta (chemokine CC) family.	0.413
CD247	CD3D	ENSMMUP00000059589	ENSMMUP00000023161	CD247 molecule.	Ig_4 domain-containing protein.	0.999
CD247	CD8A	ENSMMUP00000059589	ENSMMUP00000004695	CD247 molecule.	CD8a molecule.	0.961
CD247	GNLY	ENSMMUP00000059589	ENSMMUP00000079706	CD247 molecule.	Uncharacterized protein.	0.538
CD247	GZMA	ENSMMUP00000059589	ENSMMUP00000002136	CD247 molecule.	Granzyme A; Belongs to the peptidase S1 family.	0.861
CD247	GZMB	ENSMMUP00000059589	ENSMMUP00000018888	CD247 molecule.	Granzyme B; Belongs to the peptidase S1 family.	0.697
CD247	GZMK	ENSMMUP00000059589	ENSMMUP00000026561	CD247 molecule.	Granzyme K; Belongs to the peptidase S1 family.	0.699
CD247	KLRB1	ENSMMUP00000059589	ENSMMUP00000054695	CD247 molecule.	Killer cell lectin like receptor B1.	0.829
CD247	NKG7	ENSMMUP00000059589	ENSMMUP00000031485	CD247 molecule.	Natural killer cell granule protein 7.	0.680
CD247	PRF1	ENSMMUP00000059589	ENSMMUP00000070226	CD247 molecule.	Perforin 1.	0.778