| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| DAXX | MDM2 | ENSMMUP00000065476 | ENSMMUP00000018645 | Death domain associated protein. | E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family. | 0.974 |
| DAXX | PML | ENSMMUP00000065476 | ENSMMUP00000003455 | Death domain associated protein. | Promyelocytic leukemia protein. | 0.991 |
| DAXX | RNF4 | ENSMMUP00000065476 | ENSMMUP00000055969 | Death domain associated protein. | E3 ubiquitin ligase RNF4 isoform 1. | 0.745 |
| DAXX | SUMO1 | ENSMMUP00000065476 | ENSMMUP00000045844 | Death domain associated protein. | Small ubiquitin-related modifier. | 0.970 |
| DAXX | TP53 | ENSMMUP00000065476 | ENSMMUP00000011334 | Death domain associated protein. | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...] | 0.994 |
| DAXX | UBE2I | ENSMMUP00000065476 | ENSMMUP00000065615 | Death domain associated protein. | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. | 0.945 |
| EIF4E | PML | ENSMMUP00000014489 | ENSMMUP00000003455 | Uncharacterized protein. | Promyelocytic leukemia protein. | 0.931 |
| EIF4E | SUMO1 | ENSMMUP00000014489 | ENSMMUP00000045844 | Uncharacterized protein. | Small ubiquitin-related modifier. | 0.509 |
| EIF4E | TP53 | ENSMMUP00000014489 | ENSMMUP00000011334 | Uncharacterized protein. | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...] | 0.555 |
| MDM2 | DAXX | ENSMMUP00000018645 | ENSMMUP00000065476 | E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family. | Death domain associated protein. | 0.974 |
| MDM2 | PML | ENSMMUP00000018645 | ENSMMUP00000003455 | E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family. | Promyelocytic leukemia protein. | 0.947 |
| MDM2 | RNF4 | ENSMMUP00000018645 | ENSMMUP00000055969 | E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family. | E3 ubiquitin ligase RNF4 isoform 1. | 0.476 |
| MDM2 | RUNX1 | ENSMMUP00000018645 | ENSMMUP00000075631 | E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family. | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. | 0.724 |
| MDM2 | SUMO1 | ENSMMUP00000018645 | ENSMMUP00000045844 | E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family. | Small ubiquitin-related modifier. | 0.695 |
| MDM2 | TP53 | ENSMMUP00000018645 | ENSMMUP00000011334 | E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family. | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...] | 0.999 |
| MDM2 | UBE2I | ENSMMUP00000018645 | ENSMMUP00000065615 | E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family. | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. | 0.539 |
| PML | DAXX | ENSMMUP00000003455 | ENSMMUP00000065476 | Promyelocytic leukemia protein. | Death domain associated protein. | 0.991 |
| PML | EIF4E | ENSMMUP00000003455 | ENSMMUP00000014489 | Promyelocytic leukemia protein. | Uncharacterized protein. | 0.931 |
| PML | MDM2 | ENSMMUP00000003455 | ENSMMUP00000018645 | Promyelocytic leukemia protein. | E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family. | 0.947 |
| PML | RARA | ENSMMUP00000003455 | ENSMMUP00000016393 | Promyelocytic leukemia protein. | Retinoic acid receptor alpha isoform 1. | 0.996 |
