| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CBL | CRK | ENSMMUP00000059041 | ENSMMUP00000042452 | E3 ubiquitin-protein ligase CBL. | CRK proto-oncogene, adaptor protein. | 0.997 |
| CBL | EGFR | ENSMMUP00000059041 | ENSMMUP00000046120 | E3 ubiquitin-protein ligase CBL. | Epidermal growth factor receptor; Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF, TGFA/TGF-alpha, AREG, epigen/EPGN, BTC/betacellulin, epiregulin/EREG and HBEGF/heparin-binding EGF. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues. The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades. Activates at least [...] | 0.999 |
| CBL | ERBB2 | ENSMMUP00000059041 | ENSMMUP00000064366 | E3 ubiquitin-protein ligase CBL. | Receptor protein-tyrosine kinase. | 0.872 |
| CBL | IRS4 | ENSMMUP00000059041 | ENSMMUP00000025189 | E3 ubiquitin-protein ligase CBL. | Insulin receptor substrate 4. | 0.424 |
| CBL | PIK3CA | ENSMMUP00000059041 | ENSMMUP00000006866 | E3 ubiquitin-protein ligase CBL. | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. | 0.989 |
| CBL | PIK3CB | ENSMMUP00000059041 | ENSMMUP00000011365 | E3 ubiquitin-protein ligase CBL. | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. | 0.990 |
| CBL | PIK3CD | ENSMMUP00000059041 | ENSMMUP00000068489 | E3 ubiquitin-protein ligase CBL. | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. | 0.972 |
| CBL | PIK3R1 | ENSMMUP00000059041 | ENSMMUP00000015140 | E3 ubiquitin-protein ligase CBL. | Phosphoinositide-3-kinase regulatory subunit 1. | 0.995 |
| CBL | PIK3R2 | ENSMMUP00000059041 | ENSMMUP00000004228 | E3 ubiquitin-protein ligase CBL. | Phosphatidylinositol 3-kinase regulatory subunit beta. | 0.995 |
| CBL | PIK3R3 | ENSMMUP00000059041 | ENSMMUP00000060463 | E3 ubiquitin-protein ligase CBL. | Uncharacterized protein. | 0.976 |
| CRK | CBL | ENSMMUP00000042452 | ENSMMUP00000059041 | CRK proto-oncogene, adaptor protein. | E3 ubiquitin-protein ligase CBL. | 0.997 |
| CRK | EGFR | ENSMMUP00000042452 | ENSMMUP00000046120 | CRK proto-oncogene, adaptor protein. | Epidermal growth factor receptor; Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF, TGFA/TGF-alpha, AREG, epigen/EPGN, BTC/betacellulin, epiregulin/EREG and HBEGF/heparin-binding EGF. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues. The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades. Activates at least [...] | 0.992 |
| CRK | ERBB2 | ENSMMUP00000042452 | ENSMMUP00000064366 | CRK proto-oncogene, adaptor protein. | Receptor protein-tyrosine kinase. | 0.604 |
| CRK | IRS4 | ENSMMUP00000042452 | ENSMMUP00000025189 | CRK proto-oncogene, adaptor protein. | Insulin receptor substrate 4. | 0.783 |
| CRK | PIK3CA | ENSMMUP00000042452 | ENSMMUP00000006866 | CRK proto-oncogene, adaptor protein. | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. | 0.942 |
| CRK | PIK3CB | ENSMMUP00000042452 | ENSMMUP00000011365 | CRK proto-oncogene, adaptor protein. | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. | 0.942 |
| CRK | PIK3CD | ENSMMUP00000042452 | ENSMMUP00000068489 | CRK proto-oncogene, adaptor protein. | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. | 0.942 |
| CRK | PIK3R1 | ENSMMUP00000042452 | ENSMMUP00000015140 | CRK proto-oncogene, adaptor protein. | Phosphoinositide-3-kinase regulatory subunit 1. | 0.994 |
| CRK | PIK3R2 | ENSMMUP00000042452 | ENSMMUP00000004228 | CRK proto-oncogene, adaptor protein. | Phosphatidylinositol 3-kinase regulatory subunit beta. | 0.983 |
| CRK | PIK3R3 | ENSMMUP00000042452 | ENSMMUP00000060463 | CRK proto-oncogene, adaptor protein. | Uncharacterized protein. | 0.977 |
