STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PRDM5Zinc finger protein. (630 aa)    
Predicted Functional Partners:
KNG1
Kininogen 1.
    
 
 0.682
UROS
Uroporphyrinogen III synthase.
    
 
 0.586
EDIL3
EGF like repeats and discoidin domains 3.
   
 
 0.507
BTN1A1
Butyrophilin subfamily 1 member A1.
   
 0.502
CHD6
Chromodomain helicase DNA binding protein 6.
   
 0.495
SH3RF3
SH3 domain containing ring finger 3.
   
 0.488
HDAC1
Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.
    
 0.486
RUNX1T1
RUNX1 partner transcriptional co-repressor 1.
   
 0.481
PRDM8
PR/SET domain 8.
    
 
 0.455
PCOLCE2
Procollagen C-endopeptidase enhancer 2.
      
 0.454
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.