STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LSP1Lymphocyte specific protein 1. (341 aa)    
Predicted Functional Partners:
KSR1
Kinase suppressor of ras 1.
    
 0.928
HLA-E
Major histocompatibility complex, class I, E; Belongs to the MHC class I family.
    
   0.706
CD209
CD209 antigen; Pathogen-recognition receptor expressed on the surface of immature dendritic cells (DCs) and involved in initiation of primary immune response. Thought to mediate the endocytosis of pathogens which are subsequently degraded in lysosomal compartments. The receptor returns to the cell membrane surface and the pathogen-derived antigens are presented to resting T-cells via MHC class II proteins to initiate the adaptive immune response. Probably recognizes in a calcium- dependent manner high mannose N-linked oligosaccharides in a variety of pathogen antigens (By similarity).
    
 
 0.685
MED27
Mediator of RNA polymerase II transcription subunit 27.
      
 0.590
ATG16L1
WD_REPEATS_REGION domain-containing protein.
      
 0.554
PI4K2A
Phosphatidylinositol 4-kinase type 2 alpha.
      
 0.538
TOX3
TOX high mobility group box family member 3.
      
 0.505
PSMC3
26S protease regulatory subunit 6A; Belongs to the AAA ATPase family.
    
 0.474
EHD4
EH domain-containing protein 4; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.
      
 0.472
NHLRC2
NHL repeat containing 2.
    
 0.464
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.