Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SIPA1L3Signal induced proliferation associated 1 like 3. (1777 aa)    
Predicted Functional Partners:
SIPA1L1
Signal-induced proliferation-associated 1-like protein 1.
   
   0.716
PIM3
Protein kinase domain-containing protein.
    
 0.700
SIPA1
Signal-induced proliferation-associated protein 1.
    
   0.698
SIPA1L2
Signal induced proliferation associated 1 like 2.
    
 
 0.678
C10orf71
Chromosome 10 open reading frame 71.
     
 0.620
KCNA3
Potassium voltage-gated channel subfamily A member 3; Belongs to the potassium channel family.
   
 
 0.613
LOC704010
14_3_3 domain-containing protein; Belongs to the 14-3-3 family.
    
  0.602
YWHAQ
14-3-3 protein theta; Belongs to the 14-3-3 family.
    
  0.602
YWHAZ
14-3-3 protein zeta/delta; Belongs to the 14-3-3 family.
    
  0.578
PLK3
Serine/threonine-protein kinase PLK.
    
 
 0.565
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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