STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FCER1GFc fragment of IgE receptor Ig. (86 aa)    
Predicted Functional Partners:
SYK
Tyrosine-protein kinase.
   
 0.997
FCER1A
Fc fragment of IgE receptor Ia.
   
 
 0.989
MS4A2
Uncharacterized protein.
   
 
 0.988
CLEC4E
C-type lectin domain family 4 member E.
   
 0.986
CLEC6A
C-type lectin domain containing 6A.
   
 0.985
CLEC4D
C-type lectin domain family 4 member D.
   
 0.980
ZAP70
Tyrosine-protein kinase.
   
 0.979
LOC106994860
IG domain-containing protein.
   
 0.979
LYN
Tyrosine-protein kinase.
   
 0.977
TYROBP
TYRO protein tyrosine kinase-binding protein; Adapter protein which non-covalently associates with activating receptors found on the surface of a variety of immune cells to mediate signaling and cell activation following ligand binding by the receptors (By similarity). TYROBP is tyrosine-phosphorylated in the ITAM domain following ligand binding by the associated receptors which leads to activation of additional tyrosine kinases and subsequent cell activation (By similarity). Also has an inhibitory role in some cells (By similarity). Non-covalently associates with activating receptors [...]
   
  
 0.968
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.